Nitric Oxide radical scavenging assay of bioactive compounds present in methanol Extract of Centella asiatica
نویسندگان
چکیده
Centella asiatica L. has been used as a medicinal herb for thousands of years in India, China, Sri lanka, Nepal and Madagascar. Centella asiatica is one of the chief herbs for treating skin problems, to heal wounds, for revitalizing the nerves and brain cells, hence primarily known as a "Brain food" in India. In India, it is described under the name of Mandukaparni and used in Ayurveda medicine. Methanol extract of Centella asiatica was screened to evaluate free radical scavenging effect. The extract exhibited significant reducing power and free radical scavenging effect on nitric oxide radicals. This antioxidant activity was concentration dependent which were compared with standard antioxidants such as ascorbic acid. The highest free radical scavenging effect of the extract was observed at concentration of 200 μg/ml and the IC50 value of extract was 442. 68 μg/ml. © 2011 Universal Research Publications. All rights reserved
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